Brain-derived neurotrophic factor: a biomarker for obsessive-compulsive disorder?
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چکیده
منابع مشابه
Brain-derived neurotrophic factor: a biomarker for obsessive-compulsive disorder?
Citation: Oliveira-Maia AJ and Castro-Rodrigues P (2015) Brain-derived neurotrophic factor: a biomarker for obsessive-compulsive disorder? Front. Suliman et al. (2013) have performed a meta-analysis of studies comparing brain-derived neu-rotrophic factor (BDNF) levels between patients with anxiety disorders and healthy controls. BDNF is initially synthesized as a precursor (pre-pro-BDNF) that i...
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Background: Obsessive-Compulsive Disorder (OCD) is a serious neuropsychiatric disorder. The clinical prominence of the OCD symptoms dimensions and Brain-Derived Neurotrophic Factor (BDNF) Val66Met polymorphism are of significant importance. Objectives: The present study aimed to investigate the symptom dimensions and BDNF val66Met polymorphism genotype in Iranian patients with OCD. Materia...
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In this cross-sectional study, we assessed the levels of neurotrophins (NF) of patients with obsessive-compulsive disorder (OCD) in different stages of treatment and their relationship with OCD clinical features. Forty patients with OCD and 40 healthy controls had Brain-Derived Neurotrophic Factor (BDNF), Nerve Growth Factor (NGF), and Glial Cell-Derived Neurotrophic Factor (GNDF) plasma levels...
متن کاملSequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder.
We evaluated a possible association between the brain-derived neurotrophic factor (BDNF) gene and susceptibility to obsessive-compulsive disorder (OCD) by genotyping a number of single-nucleotide polymorphisms (SNPs) and one microsatellite marker from the extended BDNF locus in 164 triads with OCD. Extensive background linkage disequilibrium was observed at this locus. Single-locus transmission...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2015
ISSN: 1662-453X
DOI: 10.3389/fnins.2015.00134